The risk of menstrual disorders is slightly increased during the three months following administration of an anti-Covid messenger RNA vaccine, a study released this Wednesday by French health authorities suggests, while such a link remains debated in the scientific community.
The study “shows a 20% increase in the risk of menstrual bleeding requiring hospital treatment within one to three months” after receiving the Pfizer vaccine or Moderna, the Epi-Fare Institute, which brings the drugs together, summarized in a press release. Responsible for the protection of individuals in terms of authority and social security, especially health.
Since the start of the anti-Covid vaccination campaign almost two and a half years ago, many women have reported disruptions in their menstrual cycles. Based on these statements, the European Medicines Agency (EMA) included the presence of heavy menstrual bleeding as a possible side effect of the messenger RNA vaccine, which is from Pfizer/BioNTech and Moderna. However, studies on the topic remain conflicting. Epi-Fare provides arguments in favor of the existence of such a link.
Researchers identified the vaccination status of thousands of women hospitalized for heavy menstrual bleeding in 2021 and 2022. They compared their condition with a control group of women who were not treated for this reason. Finally, they conclude that the risk of such menstrual irregularities is slightly higher when a woman receives the Moderna or Pfizer vaccine for the first time, each given in two successive doses. The risk lasts for three months and then, even after a subsequent booster dose, disappears.
These results contrast with a larger study conducted in Sweden and published in Spring 2023 in the BMJ. This led to the conclusion that there is no solid evidence of a link between Covid vaccination and menstrual disorders. Asked about these different findings, the AP-Ferre researchers pointed to a difference in methodology.
They note in particular that the Swedish study considered a period of risk that began barely more than a week after the vaccination of the patients. This type of choice “can lead to a potential risk increase after a while,” explained epidemiologist Rosemary Drey-Spira, who oversaw the French study, later choosing to wait a month after the first dose of the vaccine.
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