Mango is one of the most popular fruits in the world, grown in over 100 countries and consumed by a wide variety of people.
Now, two new studies presented at the annual meeting of the American Nutrition Society show that mangoes may play a role in reducing the risk of vascular problemshelping to improve antioxidant levels in relatively healthy overweight or obese adult men and women, reports Europa Press.
“Mango contributes a variety of nutrients, phytochemicals and bioactive compounds to the diet, including 50% Daily Value (DV) of vitamin C, 15% DV of folic acid and 15% DV of copper, as well as mango. are also the predominant source of the bioactive compound mangiferin,” explained Mi Young HongPrincipal Investigator of both studies and Professor in the School of Exercise and Nutrition, College of Health and Human Services, San Diego State University (USA).
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Both crossover interventions included the same 27 overweight or obese participants (16 males, 11 females; BMI 31.8 +/- 4.1 kg/m2) aged 18 to 55 years for 28 weeks.
Participants were divided into two groups and instructed to eat either a 100 calorie mango snack (1 cup) or a 100 calorie low fat cracker snack for 12 weeks as part of their lifestyle and regular diet.
After the first 12 weeks the participants took a 4-week break, then switched groups and ate an alternative snack for another 12 weeks.. During each 12-week period, participants gave three fasting blood samples: at baseline, at weeks 4 and 12.
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When consuming mango snacks compared to low-fat biscuit snacks, after a 12-week intervention, the results of the first study showed significant positive health changes in two markers of oxidative stress, a decrease in the number of adhesion molecules-1 in vascular cells (VCAM-1) and elevated superoxide dismutase (SOD).
The results of the second study show a significant increase in glutathione peroxidase (GPX), a powerful antioxidant enzyme. Other biochemical and biomarker analyzes performed in two studies that analyzed other risk factors as well as vascular, inflammatory, and immune mediators were not significant.
“SOD and VCAM-1 play opposite roles as vascular risk factors. While the SOD enzyme reduces risk by breaking down charged oxygen molecules called superoxide radicals3 that are toxic, the VCAM-1 gene causes cells to stick to each other along vessels. mucous membranes, increasing the risk of problems. To achieve good vascular health, we want these two compounds to move in opposite directions: SOD increased and VCAM-1 decreased, which is “exactly what happened in the study. In addition, GPX works by converting hydrogen peroxide into water in the body, thereby reducing the harmful oxidative effects of hydrogen peroxide,” Yang Hong said.
With only 70 calories and over 20 different vitamins and minerals, a ¾ cup serving of mango is nutrient-dense, making it a superfood. Because mangoes are widely consumed in cultures around the world, research on their health benefits is helping to better understand their place in a healthy diet.