How the immune system can change human behavior

ANDHe the immune system can change human behavior. The smell of shellfish can make people allergic to them furiously and therefore more likely to avoid it. The same avoidance behavior is exhibited by People who develop food poisoning after eating a certain food, indicates a study conducted by scientists from the University of Yale, in the United States.


Scientists have long known that the immune system plays a key role in responses to allergens and pathogens in Wednesday, but it was not clear if this played any role in initiating this behavior towards triggers. allergic.

According to research led Yale university published in a magazine Nature, It turns out that the immune system plays a crucial role in changing human behavior. People. “We found that immunological recognition controls behavior, specifically defensive behavior against toxins that are first transmitted through antibodies and then to our brain,” said Ruslan Medzhitov, lead author of the study.


Without communication with the immune system, the brain does not warn the body about potential hazards in the environment and does not try to prevent these threats, studies show.

The team studied mice that had been sensitized to have allergic reactions to ova, a protein found in eggs. eggs from chicken. As expected, these mice tended to avoid water mixed with eggs, while control mice preferred oval water sources. They found that the aversion to ovarian water sources in sensitized mice lasted for months.

The team then checked to see if they could change behavior sensitized mice by manipulating immune system variables. They found, for example, that ovarian-allergic mice lost their aversion to protein in your water if antibodies Immunoglobulin E (IgE) cells produced by the immune system were blocked.


IgE antibodies cause release mast cells, a type of white blood cell that, along with other immune system proteins, plays a critical role in communicating with areas of the brain that control behavior aversion Without IgE as a primer, communication was interrupted so that the mice no longer avoided allergen.

Medzhitov said the results show how developed immune system to help animals avoid dangerous ecological niches. Learn how the immune system remembers potential dangers he added that it could one day help suppress an overreaction to many allergens and other pathogens. No.

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